Why Your Skin Will Love It
Your skin barrier is its first line of defence — against pollution, moisture loss, and premature ageing. The Ma:nyo Bifida Biome Complex Ampoule is a targeted night serum that harnesses the power of fermented biotechnology and multi-depth hydration to strengthen that barrier from within, delivering a radiant, dewy glow by morning.
Developed by Ma:nyo (마녀공장) — a Korean skincare brand obsessed with ingredient integrity (“endless hunger for ingredients”) — this ampoule layers Bifida Biome cultures, a 7-strain ferment blend, and 10 molecular weights of Hyaluronic Acid for barrier repair that works on multiple levels simultaneously.
✨ Key Benefits
- +83.45% skin barrier improvement — clinically measured by the Korea Institute of Dermatological Sciences (Jan–Mar 2020, 21 adult women aged 19–60). Individual results may vary.
- Reset by Night — the 7-Ferment Complex soothes and restores skin overnight, reducing redness and sensitivity while you sleep
- Shield by Day — Bifida Biome + Hyaluronic Acid maintain daytime hydration and fortify the skin’s protective barrier throughout the day
- Deep, multi-layer hydration — 10 types of Hyaluronic Acid penetrate at different skin depths for plumping results that last
- Radiance-boosting — Adenosine and Squalane work together to smooth fine lines and impart a natural, lit-from-within glow
- 100% customer satisfaction for both moisture loss prevention and anti-ageing effects (KC Skin Clinical Research Center, Nov–Dec 2020, 21 adult women aged 30–60). Individual results may vary.
- Low irritation, sensitive skin-friendly — independently dermatologist tested
🔬 Key Ingredients
| Ingredient | INCI Name | Benefit |
|---|---|---|
| Bifida Biome | Bifida Ferment Lysate | Strengthens the skin microbiome; repairs barrier function |
| 7-Ferment Complex | Fermented Saccharomyces / Lactobacillus / Aspergillus / Leuconostoc / Bacillus / Streptococcus Filtrates | Overnight soothing, restoration, and brightening |
| 10 Types of Hyaluronic Acid | Sodium Hyaluronate (multi-weight) | Multi-depth hydration; plumps and retains moisture |
| Squalane | Squalane | Lightweight emollient; locks in moisture without greasiness |
| Hydrogenated Lecithin | Hydrogenated Lecithin | Supports skin membrane integrity; enhances ingredient delivery |
| Adenosine | Adenosine | Reduces fine lines and wrinkles; anti-ageing |
| Glycerin | Glycerin | Humectant; draws moisture into skin layers |
📋 How to Use
Best used at night, before your moisturiser.
- After cleansing and toning, dispense a few drops of ampoule onto fingertips, avoiding the eye area
- Gently massage the serum into skin using upward circular motions
- Lightly pat until fully absorbed, then follow with your moisturiser or sleeping mask
💡 Pro tip: For a complete K-beauty nighttime routine, layer this ampoule between your toner/essence and your night cream. Apply morning and night during your first few weeks for best results.
📦 Product Details
| Detail | Information |
|---|---|
| Brand | Ma:nyo (마녀공장) |
| Product Name | Bifida Biome Complex Ampoule |
| Sub-title | Radiance Boosting |
| Volume | 50ml / 1.7 fl oz |
| Skin Type | All skin types; sensitive-skin tested |
| Concern | Skin barrier repair, anti-ageing, dryness, dullness |
| Key Technology | Bifida Biome + 7-Ferment Complex + 10× Hyaluronic Acid |
| Usage | Morning and/or night |
| Country of Origin | South Korea |
| Irritation Tested | Yes — Low Irritation (completed) |
| Sensitive Skin Tested | Yes — Sensitive Skin-Friendly (completed) |











